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Code: 40570

被动逃避-Step Down(跳台实验)

被动逃避(Step-Down)又称跳台实验。当提及被动逃避时,我们都采用步进测试方案。然而测量小鼠因震动感到不适而从高站台的脚步下降方案也是可行的。动物下降到带电格栏上。此测量涉及如下步骤:站台、下滑、震动。

该设备由一个竞技场型的实验箱(Cat. No. 47573) 、一个触控屏控制器40500-001和相关应用软件 40570-010

P.A系统是UB实验箱的一种,使用该触屏控制器可以操控所有的UB实验箱。
28x23cm的实验箱上部有一个7cm的平台,平台连接的发射器能够使平台摇晃。当动物下降到带电格栏上时,能够切断发射器电源,此时平台震动停止,启动延迟计数器。
延迟计数的精度为0.1秒。震动强度可以从10到100Hz(每次10Hz)进行选择。电击强度可以从 0 到3mA(每次0.1mA)进行调节。

Passive Avoidance - step down Passive Avoidance - step down

附加信息

    特征 优点
    视觉或运动功能损失模型动物的记忆测试 避免有视觉差异等因素引起的误
    平台震动诱发动物离开 简单的反应,动物运动量极小
    延迟时间计时精确到0.1秒 结果可靠
    开始: 主机控制
    停止: 主机控制
    电击:   0-2.9mA, in 0.1mA steps
    振幅: 10- 90 Hz间,9 档可调
    延迟时间: 4-digit LED 显示, 0.1s steps
    电源要求: 115/ 230V, 50/60Hz, 最大18W
    环境温度要求: 10° - 30° C
    声级: < 70 dB
    40500-001:33(w) x 25(w) x 5.5(h)cm
    47573:28(w) x 23(d) x 26(h)cm
    包装尺寸:80x60x44cm
    净重:     8Kg
    毛重:     约16Kg,
     

     

    Behavioral scientists are well acquainted with passive avoidance methods that have been used for several decades, originally by psychologists, who were interested in animal behavior.

    These procedures were later exploited by neuroscientists, who specifically perform sys-tematic studies of the behavioral changes mainly produced by brain lesions, to define the functions of different C.N.S. sections.

    The Passive Avoidance was soon extended to several other areas of research such as behavior genetics, psychopharmacology and behavioral toxicology.

    More recently, such use has become routine in animal model studies of aging and of Alz-heimer-type dementia, including the search for new drugs of potential therapeutic value, consisting of attenuation of behavioral deficits.

    The Passive Avoidance task is a one trial fear-motivated avoidance task, classically used to assess short-term or long-term memory on small laboratory animals (rodents).

    Passive Avoidance is a broad term that includes an ample selection of methods and an equally wide variety of different versions of each method.

    In our Passive Avoidance instrument one exploits the tendency to step down from a vi-brating, hence definitely uncomfortable floor section.

    40500-001 实验系统/记录仪,电击设备
    40570-010 P.A.软件
    47573 小鼠实验笼,2个完整的平台
    47573-320 7cm直径,可震动平台
    47573-321 11cm直径,可震动平台
    40500-005扩展箱
     

     

    {module Bibliography on 40570}

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媒体

{}337{/}
{module 711|category_id=43|style=mx_custom}